513.221.1100 or 800.325.7787

Office locations

Mayfield Brain & Spine

3825 Edwards Road, Suite 300

Cincinnati, Ohio 45209

The Jewish Hospital | Mercy Health Gamma Knife Center

4777 East Galbraith Road

Cincinnati, OH 45236

George T. Mandybur, MD


Areas of expertise – deep brain stimulation (DBS) for Parkinson's disease, essential tremor, dystonia, and other movement disorders; brain tumors, spine tumors; minimally invasive spine surgery, including discectomy and decompression; spinal cord stimulation and intrathecal pain pumps; trigeminal neuralgia and other facial pain; epilepsy; Gamma Knife radiosurgery


  • Undergraduate: University of Cincinnati, 1986
  • Medical School: University of Cincinnati College of Medicine, 1990
  • Residency: Neurosurgery, Loma Linda University Medical Center, Loma Linda, California, 1991-1996; General Surgery, Case Western Reserve University, Cleveland, Ohio, 1990-1991
  • Special Training: Movement Disorders and Surgical Pain Management, Loma Linda University Medical Center, 1991-1995; University of Mississippi Medical Center, Jackson, 1996-1998


American Board of Neurological Surgery

American Board of Pain Medicine


  • Mayfield Brain & Spine, Cincinnati: Neurosurgeon, 2004-present
  • Mayfield Education & Research Foundation: Board member, 2018-present
  • UC Gardner Neuroscience Institute, Cincinnati: Neurosurgeon, The Gardner Center for Parkinson's Disease and Movement Disorders, 2004-2017
  • UC College of Medicine: Associate Professor of Neurosurgery, 2004-2017; Director, Division of Functional and Stereotactic Neurosurgery, 2004-2017
  • University of Mississippi Medical Center, Jackson: Associate Professor, 2001-2004; Director of Stereotactic and Functional Neurosurgery, 1996-2004; Assistant Professor, 1996-2001

Primary hospital affiliations*

Good Samaritan Hospital, Mayfield Spine Surgery Center, The Jewish Hospital

*Mayfield is affiliated with most major hospitals in Cincinnati and Northern Kentucky

Professional memberships

  • American Association of Neurological Surgeons (AANS)
  • Congress of Neurological Surgeons (CNS)
  • CNS Section on Pain
  • American Academy of Pain Medicine
  • American College of Surgeons, Fellow
  • American Epilepsy Society
  • American Medical Association
  • American Society of Stereotactic and Functional Neurosurgeons
  • Movement Disorders Society
  • Sigma Xi Research Society


View Dr. Mandybur's publications in the PubMed database.

Related links

Physician spotlight: Dr. George Mandybur

Mayfield among First in U.S. to Offer Senza® Omnia™ Spinal Cord Stimulation System to Treat Chronic Pain

Seventeen Mayfield Specialists Named to Regional and National 'Top Doctors' Lists

Blog post: 6 Things to know about surgery for Parkinson's disease

From LOCAL12: New back therapy offers relief for patients

Mayfield neurosurgeon performs region's first laser brain surgeries for epilepsy

Ginny's story: Spinal Cord Stimulation

Don's story: Hemifacial spasm

Anisa's story: Chronic pain

Scott's story: DBS surgery for Parkinson's

Lexi's story: Reflex sympathetic dystrophy - RSD