Our faculty participate in technology development, basic science and clinical trials with special interest in translational research -- improving the pace by which laboratory findings make their way to patient care. This involves multidisciplinary collaboration among basic research laboratories and clinical subspecialties.
Clinical trials. Our office of clinical trials coordinates and conducts investigational studies for the Department of Neurosurgery. Nurses and physicians in collaboration with the staff at Cincinnati area hospitals (The University, Good Samaritan, and The Christ hospitals), work together to evaluate the safety and efficacy of devices, drugs, procedures and techniques toward improving the quality of patient care.
<view current clinical trials>
Basic science research. Our research laboratories are located at the UC Medical Center, Vontz Center and Barrett Cancer Center.
The Clinical Neurophysiology Lab studies acute brain trauma and stroke. While immediate damage caused by brain injury is irreversible, secondary events that occur in the hours and days after injury can cause further damage and be life-threatening. The premise of our research is that improvements in patient outcomes can be achieved through better means to monitor patients by allowing for early detection of secondary deterioration and delivery of therapies tailored to specific brain pathologies. more details>
Mayfield Neurotrauma Research Laboratory is engaged in brain injury research. We identify effector genes that influence functional recovery (e.g., deficits in neurological reflexes, motor coordination, and cognitive ability) after traumatic brain injury (TBI). Using behavioral pharmacology, biochemistry, histopathology and molecular techniques, we study their effects on TBI-induced inflammatory responses, neural cell death, vascular permeability and metabolism. Genes that regulate arachidonic acid metabolism following TBI are the current focus of the lab. < more details >
