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Acoustic Neuromas: Subtotal Resection & Radiosurgery
The purpose of this study is to analyze the effectiveness of subtotal removal followed by radiosurgery compared to complete removal for patients with large acoustic neuromas.
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Head and Spine Tissue Bank and Registry
The purpose of this study is to collect tissue samples from patients with tumors involving the head, brain and spine. Researchers will then use the tissue samples at some point in the future to study how to prevent, diagnose and better treat these tumors.
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Ohio Brain Tumor Study
The study is a tissue bank that includes four sites in the State of Ohio.
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Familial Intracranial Aneurysm Study
The purpose of this study is to identify the genes that may be important in the development of intracranial aneurysms. < more details >
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PRET: Patients Prone to Recurrence after Endovascular Treatment
The purpose of this research study is to compare two types of FDA approved endovascular coils used in the treatment of large aneurysms (greater than 10 mm), or if an aneurysm has recurred after a previous coiling. One coil is a platinum coil and the other is a hydrogel coil. The aim of the study is to determine if one coil has a lower recurrence rate of aneurysms and if the risks and complications are similar.
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Clazosentan in Aneurysmal Subarachnoid Hemorrhage (CONSCIOUS-3)
The purpose of this research study is to evaluate if the study drug, clazosentan, can reduce the risk of developing constriction of the blood vessels after a ruptured aneurysm in the brain which has been treated by an endovascular coiling procedure, and to determine the side effects associated with the study drug.
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ICH Removal: Minimally Invasive Surgery + rt-PA (MISTIE)
The purpose of this study is to evaluate the use of rt-PA (a clot-busting drug) after a surgical procedure to remove a blood clot from the brain after an intracerebral hemorrhage (ICH).
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Neuroform™ Stent for Wide-neck Aneurysms
The purpose of this study is to monitor the effectiveness of the Neuroform Stent in treating wide-neck aneurysms in the brain.
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Wingspan™ Stent for Blocked Brain Arteries
The purpose of this study is to monitor the effectiveness of the Wingspan Stent System to open arteries in the brain that have become blocked by a clot or narrowed by plaque.
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CORDIS ENTERPRISE™ Vascular Reconstruction Device & Delivery System
The purpose of this study is to monitor the effectiveness of the Cordis Enterprise Device in treating aneurysms in the brain.
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Onyx Liquid Embolic System HD-500
The purpose of this study is to monitor the effectiveness of the Onyx Liquid Embolic System in treating aneurysms in the brain.
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Target Imaging for Assistance in Treatment of Parkinson's
The purpose of this study is to determine whether sophisticated new imaging technologies can help pinpoint placement of deep brain stimulation electrodes in patients with Parkinson's Disease.
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Spreading Depression
The purpose of this study is to examine a form of brain seizure activity and its impact on recovery from brain injury.
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Monitoring of Delayed Ischemia after Subarachnoid Hemorrhage
The purpose of this research study is to determine whether cortical spreading depolarizations (CSD) are associated with delayed infarction and neurologic deficits after subarachnoid hemorrhage. The predictive value of CSD, measured by electrocorticography, will be compared with vasospasm.
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SLV334 in Traumatic Brain Injury
The primary purpose of this research study is to determine the safety of the study drug, SLV334, as compared to placebo (inactive study drug), for patients that have suffered a severe traumatic brain injury (TBI). The secondary purpose of this study is to determine if patients will have improved long-term functional and neurological outcome.
